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Publications

Mizbani, A., Luca, E., Rushing, E. J., & Krützfeldt, J. (2016). MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration Development, 143, 4137–4148. https://doi.org/10.1242/dev.136051
Galimov, A., Merry, T. L., Luca, E., Rushing, E. J., Mizbani, A., Turcekova, K., Hartung, A., Croce, C. M., Ristow, M., & Krützfeldt, J. (2016). microRNA-29a in adult muscle stem cells controls skeletal muscle regeneration during injury and exercise downstream of fibroblast growth factor-2 Stem Cells, 34, 768–780. https://doi.org/10.1002/stem.2281
Hruska-Plochan, M., Li, B., Kyburz, D., Krützfeldt, J., Landmesser, U., Aguzzi, A., & Polymenidou, M. (2015). New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases Swiss Medical Weekly, w14192. https://doi.org/10.4414/smw.2015.14192

Aguzzi Group
Krützfeldt Group
Polymenidou Group
Stoffel Group
Landmesser Group
Kyburz Group

Aguzzi Group

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ZORA Publication List

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Frontzek, K., Carta, M., Losa, M., Epskamp, M., Meisl, G., Anane, A., Brandel, J.-P., Camenisch, U., Castilla, J., Haïk, S., Knowles, T., Lindner, E., Lutterotti, A., Minikel, E. V., Roiter, I., Safar, J. G., Sanchez-Valle, R., Žáková, D., Hornemann, S., & Aguzzi, A. (2020). Autoantibodies against the prion protein in individuals with PRNP mutations Neurology, 95, e2028–e2037. https://doi.org/10.1212/wnl.0000000000009183
Scheckel, C., Imeri, M., Schwarz, P., & Aguzzi, A. (2020). Ribosomal profiling during prion disease uncovers progressive translational derangement in glia but not in neurons ELife, 9, e62911. https://doi.org/10.7554/elife.62911
Senatore, A., Frontzek, K., Emmenegger, M., Chincisan, A., Losa, M., Reimann, R., Horny, G., Guo, J., Fels, S., Sorce, S., Zhu, C., George, N., Ewert, S., Pietzonka, T., Hornemann, S., & Aguzzi, A. (2020). Protective anti‐prion antibodies in human immunoglobulin repertoires EMBO Molecular Medicine, e12739. https://doi.org/10.15252/emmm.202012739
Sorce, S., Nuvolone, M., Russo, G., Chincisan, A., Heinzer, D., Avar, M., Pfammatter, M., Schwarz, P., Delic, M., Müller, M., Hornemann, S., Sanoudou, D., Scheckel, C., & Aguzzi, A. (2020). Genome-wide transcriptomics identifies an early preclinical signature of prion infection PLoS Pathogens, 16, e1008653. https://doi.org/10.1371/journal.ppat.1008653
Liu, Y., & Aguzzi, A. (2019). NG2 glia are required for maintaining microglia homeostatic state Glia, glia.23721. https://doi.org/10.1002/glia.23721
Hornemann, S., Schwarz, P., Rushing, E. J., Connolly, M. D., Zuckermann, R. N., Yam, A. Y., & Aguzzi, A. (2019). Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads PLoS ONE, 14, e0216013. https://doi.org/10.1371/journal.pone.0216013
Zhu, C., Li, Z., Li, B., Pfammatter, M., Hornemann, S., & Aguzzi, A. (2019). Unaltered prion disease in mice lacking developmental endothelial locus–1 Neurobiology of Aging, 76, 208–213. https://doi.org/10.1016/j.neurobiolaging.2019.01.003
Zhu, C., Li, B., Frontzek, K., Liu, Y., & Aguzzi, A. (2019). SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease Journal of Experimental Medicine, jem.20171885. https://doi.org/10.1084/jem.20171885
Pease, D., Scheckel, C., Schaper, E., Eckhardt, V., Emmenegger, M., Xenarios, I., & Aguzzi, A. (2019). Genome-Wide Identification of microRNAs Regulating the Human Prion Protein Brain Pathology, 29, 232–244. https://doi.org/10.1111/bpa.12679
Liu, Y., Sorce, S., Nuvolone, M., Domange, J., & Aguzzi, A. (2018). Lymphocyte activation gene 3 (Lag3) expression is increased in prion infections but does not modify disease progression Scientific Reports, 8, 14600. https://doi.org/10.1038/s41598-018-32712-8
Kara, E., Marks, J. D., & Aguzzi, A. (2018). Toxic Protein Spread in Neurodegeneration: Reality versus Fantasy Trends in Molecular Medicine, 24, 1007–1020. https://doi.org/10.1016/j.molmed.2018.09.004
Keller, A., Nuvolone, M., Abakumova, I., Chincisan, A., Reimann, R., Avar, M., Heinzer, D., Hornemann, S., Wagner, J., Kirschenbaum, D., Voigt, F. F., Zhu, C., Regli, L., Helmchen, F., & Aguzzi, A. (2018). Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier PLoS Pathogens, 14, e1007424. https://doi.org/10.1371/journal.ppat.1007424
Scheckel, C., & Aguzzi, A. (2018). Prions, prionoids and protein misfolding disorders Nature Reviews. Genetics, 19, 405–418. https://doi.org/10.1038/s41576-018-0011-4
Reimann, R. R., & Aguzzi, A. (2018). Intrinsic Toxicity of Antibodies to the Globular Domain of the Prion Protein Biological Psychiatry, 84, e51–e52. https://doi.org/10.1016/j.biopsych.2018.01.028
Baral, P. K., Swayampakula, M., Aguzzi, A., & James, M. N. G. (2018). Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion FEBS Journal, 285, 1701–1714. https://doi.org/10.1111/febs.14438
Ackerman, S. D., Luo, R., Poitelon, Y., Mogha, A., Harty, B. L., D’Rozario, M., Sanchez, N. E., Lakkaraju, A. K. K., Gamble, P., Li, J., Qu, J., MacEwan, M. R., Ray, W. Z., Aguzzi, A., Feltri, M. L., Piao, X., & Monk, K. R. (2018). GPR56/ADGRG1 regulates development and maintenance of peripheral myelin Journal of Experimental Medicine, 215, 941–961. https://doi.org/10.1084/jem.20161714
Goniotaki, D., Lakkaraju, A. K. K., Shrivastava, A. N., Bakirci, P., Sorce, S., Senatore, A., Marpakwar, R., Hornemann, S., Gasparini, F., Triller, A., & Aguzzi, A. (2017). Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity PLoS Pathogens, 13, e1006733. https://doi.org/10.1371/journal.ppat.1006733
Pfammatter, M., Andreasen, M., Meisl, G., Taylor, C. G., Adamcik, J., Bolisetty, S., Sanchez-Ferrer, A., Klenerman, D., Dobson, C. M., Mezzenga, R., Knowles, T. P. J., Aguzzi, A., & Hornemann, S. (2017). Absolute Quantification of Amyloid Propagons by Digital Microfluidics Analytical Chemistry, 89, 12306–12313. https://doi.org/10.1021/acs.analchem.7b03279
Nuvolone, M., Paolucci, M., Sorce, S., Kana, V., Moos, R., Matozaki, T., & Aguzzi, A. (2017). Prion pathogenesis is unaltered in the absence of SIRPα-mediated “don’t-eat-me” signaling. PLoS ONE, 12, e0177876. https://doi.org/10.1371/journal.pone.0177876
Wulf, M.-A., Senatore, A., & Aguzzi, A. (2017). The biological function of the cellular prion protein: an update BMC Biology, 15, 34. https://doi.org/10.1186/s12915-017-0375-5
Ballmer, B. A., Moos, R., Liberali, P., Pelkmans, L., Hornemann, S., & Aguzzi, A. (2017). Modifiers of prion protein biogenesis and recycling identified by a highly-parallel endocytosis kinetics assay Journal of Biological Chemistry, 292, 8356–8368. https://doi.org/10.1074/jbc.M116.773283
Leske, H., Hornemann, S., Herrmann, U. S., Zhu, C., Dametto, P., Li, B., Laferriere, F., Polymenidou, M., Pelczar, P., Reimann, R. R., Schwarz, P., Rushing, E. J., Wüthrich, K., & Aguzzi, A. (2017). Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein PLoS ONE, 12, e0170503. https://doi.org/10.1371/journal.pone.0170503
Nuvolone, M., Schmid, N., Miele, G., Sorce, S., Moos, R., Schori, C., Beerli, R. R., Bauer, M., Saudan, P., Dietmeier, K., Lachmann, I., Linnebank, M., Martin, R., Kallweit, U., Kana, V., Rushing, E. J., Budka, H., & Aguzzi, A. (2017). Cystatin F is a biomarker of prion pathogenesis in mice PLoS ONE, 12, e0171923. https://doi.org/10.1371/journal.pone.0171923
Frontzek, K., Pfammatter, M., Sorce, S., Senatore, A., Schwarz, P., Moos, R., Frauenknecht, K., Hornemann, S., & Aguzzi, A. (2016). Neurotoxic antibodies against the prion protein do not trigger prion replication PLoS ONE, 11, e0163601. https://doi.org/10.1371/journal.pone.0163601
Küffer, A., Lakkaraju, A. K. K., Mogha, A., Petersen, S. C., Airich, K., Doucerain, C., Marpakwar, R., Bakirci, P., Senatore, A., Monnard, A., Schiavi, C., Nuvolone, M., Grosshans, B., Hornemann, S., Bassilana, F., Monk, K. R., & Aguzzi, A. (2016). The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6 Nature, 536, 464–468. https://doi.org/10.1038/nature19312
Zhu, C., Herrmann, U. S., Falsig, J., Abakumova, I., Nuvolone, M., Schwarz, P., Frauenknecht, K., Rushing, E. J., & Aguzzi, A. (2016). A neuroprotective role for microglia in prion diseases Journal of Experimental Medicine, 213, 1047–1059. https://doi.org/10.1084/jem.20151000
Aguzzi, A., & Altmeyer, M. (2016). Phase separation: linking cellular compartmentalization to disease Trends in Cell Biology, 26, 547–558. https://doi.org/10.1016/j.tcb.2016.03.004
Theocharides, A. P., Lundberg, P., Lakkaraju, A. K. K., Lysenko, V., Myburgh, R., Aguzzi, A., Skoda, R. C., & Manz, M. G. (2016). Homozygous Calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency Blood, 127, 3253–3259. https://doi.org/10.1182/blood-2016-02-696310
Aguzzi, A., & Lakkaraju, A. K. K. (2016). Cell biology of prions and prionoids: a status report Trends in Cell Biology, 26, 40–51. https://doi.org/10.1016/j.tcb.2015.08.007
Nuvolone, M., Hermann, M., Sorce, S., Russo, G., Tiberi, C., Schwarz, P., Minikel, E., Sanoudou, D., Pelczar, P., & Aguzzi, A. (2016). Strictly co-isogenic C57BL/6J-Prnp−/−mice: A rigorous resource for prion science Journal of Experimental Medicine, 213, 313–327. https://doi.org/10.1084/jem.20151610
Reimann, R. R., Sonati, T., Hornemann, S., Herrmann, U. S., Arand, M., Hawke, S., & Aguzzi, A. (2016). Differential toxicity of antibodies to the prion protein PLoS Pathogens, 12, e1005401. https://doi.org/10.1371/journal.ppat.1005401
Nuvolone, M., & Aguzzi, A. (2015). Altered monoaminergic systems and depressive-like behavior in congenic prion protein nnock-out mice Journal of Biological Chemistry, 290, 26350. https://doi.org/10.1074/jbc.L115.689117
Herrmann, U. S., Schütz, A. K., Shirani, H., Huang, D., Saban, D., Nuvolone, M., Li, B., Ballmer, B., Åslund, A. K. O., Mason, J. J., Rushing, E., Budka, H., Nystrom, S., Hammarstrom, P., Böckmann, A., Caflisch, A., Meier, B. H., Nilsson, K. P. R., Hornemann, S., & Aguzzi, A. (2015). Structure-based drug design identifies polythiophenes as antiprion compounds Science Translational Medicine, 7, 299ra123. https://doi.org/10.1126/scitranslmed.aab1923
Herrmann, U. S., Sonati, T., Falsig, J., Reimann, R. R., Dametto, P., O’Connor, T., Li, B., Lau, A., Hornemann, S., Sorce, S., Wagner, U., Sanoudou, D., & Aguzzi, A. (2015). Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways PLoS Pathogens, 11, e1004662. https://doi.org/10.1371/journal.ppat.1004662
Dametto, P., Lakkaraju, A. K. K., Bridel, C., Villiger, L., O’Connor, T., Herrmann, U. S., Pelczar, P., Rülicke, T., McHugh, D., Adili, A., & Aguzzi, A. (2015). Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP PLoS ONE, 10, e0117412. https://doi.org/10.1371/journal.pone.0117412
Nuvolone, M., Sorce, S., Schwarz, P., & Aguzzi, A. (2015). Prion pathogenesis in the absence of NLRP3/ASC inflammasomes PLoS ONE, 10, e0117208. https://doi.org/10.1371/journal.pone.0117208
Zhu, C., Herrmann, U. S., Li, B., Abakumova, I., Moos, R., Schwarz, P., Rushing, E. J., Colonna, M., & Aguzzi, A. (2015). Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains Neurobiology of Aging, 36, 1994–2003. https://doi.org/10.1016/j.neurobiolaging.2015.02.019
Aguzzi, A. (2014). Neurodegeneration: Alzheimer’s disease under strain. Nature, 512, 32–34. https://doi.org/10.1038/512032a
Franklin, B. S., Bossaller, L., De Nardo, D., Ratter, J. M., Stutz, A., Engels, G., Brenker, C., Nordhoff, M., Mirandola, S. R., Al-Amoudi, A., Mangan, M. S., Zimmer, S., Monks, B. G., Fricke, M., Schmidt, R. E., Espevik, T., Jones, B., Jarnicki, A. G., Hansbro, P. M., … Latz, E. (2014). The adaptor ASC has extracellular and “prionoid” activities that propagate inflammation. Nature Immunology, 15, 727–737. https://doi.org/10.1038/ni.2913
Sorce, S., Nuvolone, M., Keller, A., Falsig, J., Varol, A., Schwarz, P., Bieri, M., Budka, H., & Aguzzi, A. (2014). The role of the NADPH oxidase NOX2 in prion pathogenesis PLoS Pathogens, 10, e1004531. https://doi.org/10.1371/journal.ppat.1004531
O’Connor, T., & Aguzzi, A. (2013). Prions and lymphoid organs: Solved and remaining mysteries Prion, 7, 157–163. https://doi.org/10.4161/pri.23536
Sonati, T., Reimann, R. R., Falsig, J., Baral, P. K., O’Connor, T., Hornemann, S., Yaganoglu, S., Li, B., Herrmann, U. S., Wieland, B., Swayampakula, M., Rahman, M. H., Das, D., Kav, N., Riek, R., Liberski, P. P., James, M. N. G., & Aguzzi, A. (2013). The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein Nature, 501, 102–106. https://doi.org/10.1038/nature12402
Aguzzi, A., Barres, B. A., & Bennett, M. L. (2013). Microglia: scapegoat, saboteur, or something else? Science, 339, 156–161. https://doi.org/10.1126/science.1227901
Nuvolone, M., Kana, V., Hutter, G., Sakata, D., Mortin-Toth, S. M., Russo, G., Danska, J. S., & Aguzzi, A. (2013). SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells Journal of Experimental Medicine, 210, 2539–2552. https://doi.org/10.1084/jem.20131274
Sponarova, J., Nuvolone, M., Whicher, C., Frei, N., Kana, V., Schwarz, P., Westermark, G. T., & Aguzzi, A. (2013). Efficient amyloid a clearance in the absence of immunoglobulins and complement factors American Journal of Pathology, 182, 1297–1307. https://doi.org/10.1016/j.ajpath.2012.12.035
Aguzzi, A., Nuvolone, M., & Zhu, C. (2013). The immunobiology of prion diseases Nature Reviews. Immunology, 13, 888–902. https://doi.org/10.1038/nri3553
Aguzzi, A., & Calella, A. M. (2009). Prions: protein aggregation and infectious diseases Physiological Reviews, 89, 1105–1152. https://doi.org/10.1152/physrev.00006.2009
Polymenidou, M., Moos, R., Scott, M., Sigurdson, C., Shi, Y. Z., Yajima, B., Hafner-Bratkovic, I., Jerala, R., Hornemann, S., Wuthrich, K., Bellon, A., Vey, M., Garen, G., James, M. N. G., Kav, N., & Aguzzi, A. (2008). The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes PLoS ONE, 3, e3872. https://doi.org/10.1371/journal.pone.0003872

Krützfeldt Group

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Publications

Gorski, T., Mathes, S., & Krützfeldt, J. (2018). Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control Journal of Cachexia, Sarcopenia and Muscle, 9, 384–399. https://doi.org/10.1002/jcsm.12277
Mizbani, A., Luca, E., Rushing, E. J., & Krützfeldt, J. (2016). MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration Development, 143, 4137–4148. https://doi.org/10.1242/dev.136051
Krützfeldt, J. (2016). Strategies to use microRNAs as therapeutic targets Best Practice & Research : Clinical Endocrinology & Metabolism, 30, 551–561. https://doi.org/10.1016/j.beem.2016.07.004
Galimov, A., Merry, T. L., Luca, E., Rushing, E. J., Mizbani, A., Turcekova, K., Hartung, A., Croce, C. M., Ristow, M., & Krützfeldt, J. (2016). microRNA-29a in adult muscle stem cells controls skeletal muscle regeneration during injury and exercise downstream of fibroblast growth factor-2 Stem Cells, 34, 768–780. https://doi.org/10.1002/stem.2281
Galimov, A., Hartung, A., Trepp, R., Mader, A., Flück, M., Linke, A., Blüher, M., Christ, E., & Krützfeldt, J. (2015). Growth hormone replacement therapy regulates microRNA-29a and targets involved in insulin resistance Journal of Molecular Medicine, 93, 1369–1379. https://doi.org/10.1007/s00109-015-1322-y

Krützfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M. Silencing of microRNAs in vivo with 'antagomirs'. Nature. 2005 Dec 1;438(7068):685-9.

Krützfeldt J, Poy MN, Stoffel M. Strategies to determine the biological function of microRNAs. Nat Genet. 2006 Jun;38 Suppl 1:S14-9.

Krützfeldt J, Stoffel M. MicroRNAs: A new class of regulatory genes affecting metabolism. Cell Metab. 2006 Jul;4(1):9-12.

Krützfeldt J, Kuwajima S, Braich R, Rajeev KG, Pena J, Tuschl T, Manoharan M, Stoffel M. Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Res. 2007 April; 35(9):2885-92.

Krützfeldt J, Rösch N, Hausser J, Manoharan M, Zavolan M, Stoffel M. MicroRNA-194 is a target of transcription factor 1 (Tcf1, Hnf1α) in adult liver and controls expression of frizzled-6. Hepatology. 2012 Jan;55(1):98-107.

Polymenidou Group

http://www.imls.uzh.ch/en/research/polymenidou/publ.html

ZORA Publication List

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Publications

Leske, H., Hornemann, S., Herrmann, U. S., Zhu, C., Dametto, P., Li, B., Laferriere, F., Polymenidou, M., Pelczar, P., Reimann, R. R., Schwarz, P., Rushing, E. J., Wüthrich, K., & Aguzzi, A. (2017). Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein PLoS ONE, 12, e0170503. https://doi.org/10.1371/journal.pone.0170503
Hock, E.-M., & Polymenidou, M. (2016). Prion-like propagation as a pathogenic principle in frontotemporal dementia Journal of Neurochemistry, 138 Supp, 163–183. https://doi.org/10.1111/jnc.13668

Polymenidou M*, Lagier-Tourenne C*, Hutt KR*, Huelga SC, Moran J, Liang TY, Ling SC, Sun E, Wancewicz E, Mazur C, Kordasiewicz H, Sedaghat Y, Donohue JP, Shiue L, Bennett CF, Yeo GW, Cleveland DW (2011) Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nature Neurosc, 14, 459–468 [*equal contribution]

Polymenidou M, Cleveland DW (2011) The Seeds of Neurodegeneration: Prion-like Spreading in ALS. Cell, 147, 498-508

Polymenidou M, Cleveland DW (2012) Prion-like spread of protein aggregates in neurodegeneration. Journal of Exp Med, 209, 889-93

Lagier-Tourenne C*, Polymenidou M*, Hutt KR*, Vu AQ, Clutario K, Baughn M, Huelga SC, Ling SC, Liang TY, Mazur C, Wancewicz E, Kim AS, Watt A, Freier S, Hicks GG, Donohue JP, Shiue L, Bennett CF, Ravits J, Cleveland DW and Yeo GW (2012) Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nature Neurosc, 15, 1488-97 [*equal contribution]

Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling S-C, Zhu Q, Polymenidou M, Drenner K, Artates JW, McAlonis-Downes M, Markmiller S, Hutt KR, Pizzo DP, Cady J, Harms MB, Baloh RH, Vandenberg SR, Yeo GW, Fu X-D, Bennett CF, Cleveland DW, Ravits J (2013) Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. PNAS, 110, 47, E4530-39

Stoffel Group

Selected publications

LaPierre MP and Stoffel M (2017). MicroRNAs as stress regulators in pancreatic beta cells and diabetes. Molecular Metabolism 6:1010-1023.

Landmesser Group

ZORA Publication List

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Mach, F., Koskinas, K. C., Roeters van Lennep, J. E., Tokgözoğlu, L., Badimon, L., Baigent, C., Benn, M., Binder, C. J., Catapano, A. L., De Backer, G. G., Delgado, V., Fabin, N., Ference, B. A., Graham, I. M., Landmesser, U., Laufs, U., Mihaylova, B., Nordestgaard, B. G., Richter, D. J., … et al. (2025). 2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias European Heart Journal, 46, 4359–4378. https://doi.org/10.1093/eurheartj/ehaf190
Heidecker, B., Libby, P., Vassiliou, V. S., Roubille, F., Vardeny, O., Hassager, C., Gatzoulis, M. A., Mamas, M. A., Cooper, L. T., Schoenrath, F., Metra, M., Amir, O., Solomon, S. D., Landmesser, U., & Lüscher, T. F. (2025). Vaccination as a new form of cardiovascular prevention: a European Society of Cardiology clinical consensus statement European Heart Journal, 46, 3518–3531. https://doi.org/10.1093/eurheartj/ehaf384
Landmesser, U., Thum, T., Tokgözoğlu, L., Guzik, T. J., Cosentino, F., Hajjar, R., Goncalves, A., Laguna-Fernandez, A., Nioi, P., Prochaska, J. H., Rocha, R., Kathiresan, S., März Julian Werner, Maurer, M. S., O’Donnell, C. J., Passacquale, G., Tavridou, A., Van Heetvelde, M., Himmelmann, A., … Lüscher, T. F. (2025). Pharmacotherapy of cardiovascular diseases from herbs and pills to nucleic acids European Heart Journal, ehaf520. https://doi.org/10.1093/eurheartj/ehaf520
Müller, M. L., Brand, A., Mattig, I., Spethmann, S., Messroghli, D., Hahn, K., Violano, M., Mitchell, J., Hare, J. M., FRUSTACI, A., Klingel, K., Lüscher, T. F., Landmesser, U., & Heidecker, B. (2025). Myocardial Inflammation in Cardiac Transthyretin Amyloidosis: Prevalence and Potential Prognostic Implications Circulation : Heart Failure, 18, e012146. https://doi.org/10.1161/circheartfailure.124.012146
Ponikowski, P., Friede, T., von Bardeleben, R. S., Butler, J., Shahzeb Khan, M., Diek, M., Heinrich, J., Geyer, M., Placzek, M., Ferrari, R., Abraham, W. T., Alfieri, O., Auricchio, A., Bayes-Genis, A., Cleland, J. G. F., Filippatos, G., Gustafsson, F., Haverkamp, W., Kelm, M., … et al. (2024). Hospitalization of Symptomatic Patients With Heart Failure and Moderate to Severe Functional Mitral Regurgitation Treated With MitraClip: Insights From RESHAPE-HF2 Journal of the American College of Cardiology, 84, 2347–2363. https://doi.org/10.1016/j.jacc.2024.08.027
Anker, S. D., Friede, T., von Bardeleben, R.-S., Butler, J., Khan, M.-S., Diek, M., Heinrich, J., Geyer, M., Placzek, M., Ferrari, R., Abraham, W. T., Alfieri, O., Auricchio, A., Bayes-Genis, A., Cleland, J. G. F., Filippatos, G., Gustafsson, F., Haverkamp, W., Kelm, M., … et al. (2024). Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation New England Journal of Medicine, 391, 1799–1809. https://doi.org/10.1056/NEJMoa2314328
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Al-Hindwan, H. S. A., Landmesser, U., Stähli, B., Alushi, B., Curio, J., Neumann, T., Jung, F., Lendlein, A., Jacobs, S., & Reinthaler, M. (2018). The predictive value of a modified Carpentier classification in patients with coincidental mitral regurgitation undergoing TAVI for severe aortic valve stenosis1 Clinical Hemorheology and Microcirculation, 70, 15–25. https://doi.org/10.3233/CH-189906
Ference, B. A., Cannon, C. P., Landmesser, U., Lüscher, T. F., Catapano, A. L., & Ray, K. K. (2018). Reduction of low density lipoprotein-cholesterol and cardiovascular events with proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors and statins: an analysis of FOURIER, SPIRE, and the Cholesterol Treatment Trialists Collaboration European Heart Journal, 39, 2540–2545. https://doi.org/10.1093/eurheartj/ehx450
Stähli, B. E., Reinthaler, M., Leistner, D. M., Landmesser, U., & Lauten, A. (2018). Transcatheter Aortic Valve Replacement and Concomitant Mitral Regurgitation Frontiers in Cardiovascular Medicine, 5, 74. https://doi.org/10.3389/fcvm.2018.00074
Rillig, A., Bellmann, B., Skurk, C., Leistner, D. M., Haeusler, K. G., Lin, T., Geran, R., Koehler, L., Guttmann, S., Steffens, D., Kasner, M., Jakob, P., Tscholl, V., Roser, M., Lenz, K., Villringer, K., Park, J.-W., Fiebach, J. B., & Landmesser, U. (2018). Left atrial appendage angiography is associated with the incidence and number of magnetic resonance imaging-detected brain lesions after percutaneous catheter-based left atrial appendage closure Heart Rhythm, 15, 3–8. https://doi.org/10.1016/j.hrthm.2017.11.015
Klingenberg, R., Aghlmandi, S., Liebetrau, C., Räber, L., Gencer, B., Nanchen, D., Carballo, D., Akhmedov, A., Montecucco, F., Zoller, S., Brokopp, C., Heg, D., Jüni, P., Marti Soler, H., Marques-Vidal, P.-M., Vollenweider, P., Dörr, O., Rodondi, N., Mach, F., … Lüscher, T. F. (2017). Cysteine-rich angiogenic inducer 61 (Cyr61): a novel soluble biomarker of acute myocardial injury improves risk stratification after acute coronary syndromes European Heart Journal, 38, 3493–3502. https://doi.org/10.1093/eurheartj/ehx640
Lempereur, M., Aminian, A., Freixa, X., Gafoor, S., Shakir, S., Omran, H., Berti, S., Santoro, G., Kefer, J., Landmesser, U., Nielsen-Kudsk, J. E., Cruz-Gonzalez, I., Kanagaratnam, P., Nietlispach, F., Ibrahim, R., Sievert, H., Schillinger, W., Park, J.-W., Gloekler, S., & Tzikas, A. (2017). Left atrial appendage occlusion in patients with atrial fibrillation and previous major gastrointestinal bleeding (from the Amplatzer Cardiac Plug Multicenter Registry) American Journal of Cardiology, 120, 414–420. https://doi.org/10.1016/j.amjcard.2017.04.046
Zewinger, S., Kleber, M. E., Rohrer, L., Lehmann, M., Triem, S., Jennings, R. T., Petrakis, I., Dressel, A., Lepper, P. M., Scharnagl, H., Ritsch, A., Thorand, B., Heier, M., Meisinger, C., de Las Heras Gala, T., Koenig, W., Wagenpfeil, S., Schwedhelm, E., Böger, R. H., … Speer, T. (2017). Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease European Heart Journal, 38, 1597–1607. https://doi.org/10.1093/eurheartj/ehx118
März, W., Kleber, M. E., Scharnagl, H., Speer, T., Zewinger, S., Ritsch, A., Parhofer, K. G., von Eckardstein, A., Landmesser, U., & Laufs, U. (2017). HDL cholesterol: reappraisal of its clinical relevance Clinical Research in Cardiology, 106, 663–675. https://doi.org/10.1007/s00392-017-1106-1
Jaguszewski, M., Aloysius, R., Wang, W., Bezerra, H. G., Hill, J., De Winter, R. J., Karjalainen, P. P., Verheye, S., Wijns, W., Lüscher, T. F., Joner, M., Costa, M., & Landmesser, U. (2017). The REMEDEE-OCT Study: An Evaluation of the Bioengineered COMBO Dual-Therapy CD34 Antibody-Covered Sirolimus-Eluting Coronary Stent Compared With a Cobalt-Chromium Everolimus-Eluting Stent in Patients With Acute Coronary Syndromes: Insights From Optical Coherence Tomography Imaging Analysis JACC. Cardiovascular Interventions, 10, 489–499. https://doi.org/10.1016/j.jcin.2016.11.040
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März, W., Kleber, M. E., Scharnagl, H., Speer, T., Zewinger, S., Ritsch, A., Parhofer, K. G., von Eckardstein, A., Landmesser, U., & Laufs, U. (2017). Klinische Bedeutung des HDL-Cholesterins Herz, 42, 58–66. https://doi.org/10.1007/s00059-016-4499-0
Templin, C., Volkmann, J., Emmert, M. Y., Mocharla, P., Müller, M., Kraenkel, N., Ghadri, J.-R., Meyer, M., Styp-Rekowska, B., Briand, S., Klingenberg, R., Jaguszewski, M., Matter, C. M., Djonov, V., Mach, F., Windecker, S., Hoerstrup, S. P., Thum, T., Lüscher, T. F., & Landmesser, U. (2017). Increased proangiogenic activity of mobilized CD34$^+$ progenitor cells of patients with acute ST-segment-elevation myocardial infarction: role of differential MicroRNA-378 expression Arteriosclerosis, Thrombosis, and Vascular Biology, 37, 341–349. https://doi.org/10.1161/ATVBAHA.116.308695
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Landmesser, U., John Chapman, M., Farnier, M., Gencer, B., Gielen, S., Hovingh, G. K., Lüscher, T. F., Sinning, D., Tokgözoğlu, L., Wiklund, O., Zamorano, J. L., Pinto, F. J., Catapano, A. L., European Society of Cardiology (ESC), & European Atherosclerosis Society (EAS). (2016). European Society of Cardiology/European Atherosclerosis Society Task Force consensus statement on proprotein convertase subtilisin/kexin type 9 inhibitors: practical guidance for use in patients at very high cardiovascular risk European Heart Journal, ehw480. https://doi.org/10.1093/eurheartj/ehw480
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., Reiner, Ž., Riccardi, G., Taskinen, M.-R., Tokgozoglu, L., Verschuren, W. M. M., Vlachopoulos, C., Wood, D. A., & Zamorano, J. L. (2016). 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias: The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)Developed with the special contribution of the European Assocciation for Cardiovascular Prevention & Rehabilitation (EACPR) European Heart Journal, 37, 2999–3058. https://doi.org/10.1093/eurheartj/ehw272
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Sutter, I., Klingenberg, R., Othman, A., Rohrer, L., Landmesser, U., Heg, D., Rodondi, N., Mach, F., Windecker, S., Matter, C. M., Lüscher, T. F., von Eckardstein, A., & Hornemann, T. (2016). Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction Atherosclerosis, 246, 130–140. https://doi.org/10.1016/j.atherosclerosis.2016.01.003
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Lüscher, T. F., Bax, J. J., Gersh, B. J., Hindricks, G., Landmesser, U., Ruschitzka, F., & Wijns, W. (2015). EHJ’s new impact factor of 15.2: a global strategy is paying off. European Heart Journal, 36, 2763–2766. https://doi.org/10.1093/eurheartj/ehv504
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Hruska-Plochan, M., Li, B., Kyburz, D., Krützfeldt, J., Landmesser, U., Aguzzi, A., & Polymenidou, M. (2015). New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases Swiss Medical Weekly, w14192. https://doi.org/10.4414/smw.2015.14192
Reiser, H., Klingenberg, R., Hof, D., Cooksley-Decasper, S., Fuchs, N., Akhmedov, A., Zoller, S., Marques-Vidal, P., Marti Soler, H., Heg, D., Landmesser, U., Rodondi, N., Mach, F., Windecker, S., Vollenweider, P., Matter, C. M., Lüscher, T. F., von Eckardstein, A., & Gawinecka, J. (2015). Circulating FABP4 Is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals Arteriosclerosis, Thrombosis, and Vascular Biology, 35, 1872–1879. https://doi.org/10.1161/ATVBAHA.115.305365
Sutter, I., Velagapudi, S., Othman, A., Riwanto, M., Manz, J., Rohrer, L., Rentsch, K., Hornemann, T., Landmesser, U., & von Eckardstein, A. (2015). Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL Atherosclerosis, 241, 539–546. https://doi.org/10.1016/j.atherosclerosis.2015.05.037
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Jaguszewski, M., Manes, C., Puippe, G., Salzberg, S., Müller, M., Falk, V., Lüscher, T. F., Luft, A., Alkadhi, H., & Landmesser, U. (2015). Cardiac CT and echocardiographic evaluation of peri-device flow after percutaneous left atrial appendage closure using the AMPLATZER cardiac plug device Catheterization and Cardiovascular Interventions, 85, 306–312. https://doi.org/10.1002/ccd.25667
Kühnast, S., van der Tuin, S. J. L., van der Hoorn, J. W. A., van Klinken, J. B., Simic, B., Pieterman, E., Havekes, L. M., Landmesser, U., Lüscher, T. F., Van Dijk, K. W., Rensen, P. C. N., Jukema, J. W., & Princen, H. M. G. (2015). Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin European Heart Journal, 36, 39–50. https://doi.org/10.1093/eurheartj/ehu319
Stähli, B. E., Nguyen-Kim, T. D. L., Gebhard, C., Erhart, L., Frauenfelder, T., Tanner, F. C., Falk, V., Landmesser, U., Nietlispach, F., Lüscher, T. F., Maier, W., & Binder, R. K. (2015). Prosthesis-specific predictors of paravalvular regurgitation after transcatheter aortic valve replacement: impact of calcification and sizing on balloon-expandable versus self-expandable transcatheter heart valves Journal of Heart Valve Disease, 24, 10–21.
Stähli, B. E., Gebhard, C., Saleh, L., Falk, V., Landmesser, U., Nietlispach, F., Maisano, F., Lüscher, T. F., Maier, W., & Binder, R. K. (2015). N-terminal pro-B-type natriuretic peptide ratio predicts mortality after transcatheter aortic valve replacement Catheterization and Cardiovascular Interventions, 85, 1240–1247. https://doi.org/10.1002/ccd.25788
Klingenberg, R., Brokopp, C. E., Grivès, A., Courtier, A., Jaguszewski, M., Pasqual, N., Vlaskou Badra, E., Lewandowski, A., Gaemperli, O., Hoerstrup, S. P., Maier, W., Landmesser, U., Lüscher, T. F., & Matter, C. M. (2015). Clonal restriction and predominance of regulatory T cells in coronary thrombi of patients with acute coronary syndromes European Heart Journal, 36, 1041–1048. https://doi.org/10.1093/eurheartj/eht543
Riwanto, M., Rohrer, L., von Eckardstein, A., & Landmesser, U. (2015). Dysfunctional HDL: from structure-function-relationships to biomarkers In A. von Eckardstein & D. Kardassis (Eds.), High Density Lipoproteins : From Biological Understanding to Clinical Exploitation (No. 224; Vol. 224, pp. 337–366). Springer. https://doi.org/10.1007/978-3-319-09665-0_10
Jaguszewski, M., Ghadri, J.-R., Seifert, B., Hiestand, T., Herrera, P., Gaemperli, O., Landmesser, U., Maier, W., Nallamothu, B. K., Windecker, S., Lüscher, T. F., & Templin, C. (2015). Drug-eluting stents vs. bare metal stents in patients with cardiogenic shock: a comparison by propensity score analysis Journal of Cardiovascular Medicine, 16, 220–229. https://doi.org/10.2459/JCM.0000000000000106
Holy, E. W., Besler, C., Reiner, M. F., Camici, G. G., Manz, J., Beer, J. H., Lüscher, T. F., Landmesser, U., & Tanner, F. C. (2014). High-density lipoprotein from patients with coronary heart disease loses anti-thrombotic effects on endothelial cells: Impact on arterial thrombus formation Thrombosis and Haemostasis, 112, 1024–1035. https://doi.org/10.1160/TH13-09-0775
Windecker, S., Kolh, P., Alfonso, F., Collet, J.-P., Cremer, J., Falk, V., Filippatos, G., Hamm, C., Head, S. J., Jüni, P., Kappetein, A. P., Kastrati, A., Knuuti, J., Landmesser, U., Laufer, G., Neumann, F.-J., Richter, D. J., Schauerte, P., Sousa Uva, M., … Witkowski, A. (2014). 2014 ESC/EACTS Guidelines on myocardial revascularization: The task force on myocardial revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) European Heart Journal, 35, 2541–2619. https://doi.org/10.1093/eurheartj/ehu278
Lüscher, T. F., Gersh, B., Hindricks, G., Landmesser, U., Ruschitzka, F., & Wijns, W. (2014). FastTrack: a key success factor for the European Heart Journal European Heart Journal, 35, 1983–1990. https://doi.org/10.1093/eurheartj/ehu251
Kratzer, Adelheid; Giral, Hector; Landmesser, Ulf (2014). High-density lipoproteins as modulators of endothelial cell functions: alterations in patients with coronary artery disease Cardiovascular Research, 103(3):350-361.
Klose, G., Beil, F. U., Dieplinger, H., von Eckardstein, A., Föger, B., Gouni-Berthold, I., Koenig, W., Kostner, G. M., Landmesser, U., Laufs, U., Leistikow, F., März, W., Merkel, M., Müller-Wieland, D., Noll, G., Parhofer, K. G., Paulweber, B., Riesen, W., Schaefer, J. R., … Windler, E. (2014). Neue AHA- und ACC-Leitlinie zur Risikoreduktion von Herz-Kreislauf-Erkrankungen durch Cholesterinsenkung Der Internist, 55, 601–606. https://doi.org/10.1007/s00108-014-3492-z
Attinger-Toller, A., Lüscher, T. F., Landmesser, U., & Nietlispach, F. (2014). Catch me if you can European Heart Journal, 35, 903. https://doi.org/10.1093/eurheartj/eht472
Gielen, S; Landmesser, U (2014). The Year in Cardiology 2013: cardiovascular disease prevention European Heart Journal, 35(5):307-312.
Lüscher, T. F., Landmesser, U., von Eckardstein, A., & Fogelman, A. M. (2014). High-density lipoprotein: Vascular protective effects, dysfunction, and potential as therapeutic target Circulation Research, 114, 171–182. https://doi.org/10.1161/CIRCRESAHA.114.300935
Kränkel, N., Lüscher, T. F., & Landmesser, U. (2014). Novel insights into vascular repair mechanisms Current Pharmaceutical Design, 20, 2430–2438. https://doi.org/10.2174/13816128113199990478
Lüscher, T. F., Gersh, B., Landmesser, U., & Ruschitzka, F. (2014). Is the panic about beta-blockers in perioperative care justified? European Heart Journal, 35, 2442–2444. https://doi.org/10.1093/eurheartj/ehu056
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Stähli, B. E., Reinthaler, M., Nguyen-Kim, T. D. L., Gebhard, C., Tasnady, H., Grünenfelder, J., Falk, V., Corti, R., Frauenfelder, T., Lüscher, T. F., Maier, W., Mullen, M. J., & Landmesser, U. (2014). Transcatheter aortic valve-in-valve implantation: Clinical outcome as defined by VARC-2 and postprocedural valve dysfunction according to the primary mode of bioprosthesis failure Journal of Invasive Cardiology, 26, 542–547.
Sudano, I., Pourmand, A., Schoenenberger-Berzins, R., Suter, P. M., Roas, S., Templin, C., Landmesser, U., Noll, G., Battegay, E., Erne, P., & Lüscher, T. F. (2014). Klinische Effekte der katheterbasierten Nierennervenablation bei therapieresistenter Hypertonie Cardiovascular Medicine, 17, 8–13. http://www.cardiovascmed.ch/docs/cvm/2014/01/en/cvm-00201.pdf
Emmert, M. Y., Puippe, G., Baumüller, S., Alkadhi, H., Landmesser, U., Plass, A., Bettex, D., Scherman, J., Grünenfelder, J., Genoni, M., Falk, V., & Salzberg, S. P. (2014). Safe, effective and durable epicardial left atrial appendage clip occlusion in patients with atrial fibrillation undergoing cardiac surgery: first long-term results from a prospective device trial European Journal of Cardio-Thoracic Surgery, 45, 126–131. https://doi.org/10.1093/ejcts/ezt204
Shroff, R., Speer, T., Colin, S., Charakida, M., Zewinger, S., Staels, B., Chinetti-Gbaguidi, G., Hettrich, I., Rohrer, L., O’Neill, F., McLoughlin, E., Long, D., Shanahan, C. M., Landmesser, U., Fliser, D., & Deanfield, J. E. (2014). HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype Journal of the American Society of Nephrology (JASN), 25, 2658–2668. https://doi.org/10.1681/ASN.2013111212
Attinger-Toller, A., Hager, P., Rickli, H., Lüscher, T. F., Landmesser, U., & Nietlispach, F. (2014). To do or not to do? Changing paradigms: value of balloon-sizing and left atrial appendage occlusion Cardiovascular Medicine, 17, 21–23. http://www.cardiovascmed.ch/docs/cvm/2014/01/en/cvm-00202.pdf
Nguyen-Kim, T. D. L., Binder, R. K., Lüscher, T. F., Falk, V., Frauenfelder, T., & Landmesser, U. (2014). TAVI in a low left main coronary artery ostium and wide aortic sinus of Valsava European Heart Journal, 35, 1791–1791. https://doi.org/10.1093/eurheartj/eht414
Ghadri, J. R., Jaguszewski, M., Sacron, A., Srikantharupan, S., Pfister, P., Siddique, A., Kaufmann, P. A., Wyss, C. A., Gämperli, O., Landmesser, U., Altwegg, L., Maier, W., Corti, R., Lüscher, T. F., & Templin, C. (2013). Current outcome of acute coronary syndromes: data from the Zurich-Acute Coronary Syndrome (Z-ACS) Registry Cardiovascular Medicine, 13, 115–122. http://www.cardiovascmed.ch/docs/cvm/2013/04/en/cvm-00156.pdf
Wagner, J., Riwanto, M., Besler, C., Knau, A., Fichtlscherer, S., Röxe, T., Zeiher, A. M., Landmesser, U., & Dimmeler, S. (2013). Characterization of levels and cellular transfer of circulating lipoprotein-bound microRNAs Arteriosclerosis, Thrombosis, and Vascular Biology, 33, 1392–1400. https://doi.org/10.1161/ATVBAHA.112.300741
Mocharla, P., Briand, S., Giannotti, G., Dörries, C., Jakob, P., Paneni, F., Lüscher, T. F., & Landmesser, U. (2013). AngiomiR-126 expression and secretion from circulating CD34+ and CD14+ PBMCs: role for pro-angiogenic effects and alterations in type-2 diabetics Blood, 121, 226–236. https://doi.org/10.1182/blood-2012-01-407106
Lüscher, T. F., Gersh, B., Hindricks, G., Landmesser, U., Nallamothu, B., Ruschitzka, F., & Wijns, W. (2013). The European Heart Journal on the move: can scientific publishing be further improved? European Heart Journal, 34, 409–415. https://doi.org/10.1093/eurheartj/ehs360
Singaraja, R. R., Sivapalaratnam, S., Landmesser, U., & et al. (2013). The impact of partial and complete loss of function mutations in endothelial lipase on hdl levels and functionality in humans Circulation. Cardiovascular Genetics, 6, 54–62. https://doi.org/10.1161/CIRCGENETICS.111.962613
Riwanto, M., & Landmesser, U. (2013). High-density lipoproteins and endothelial functions: Mechanistic insights and alterations in cardiovascular disease Journal of Lipid Research, 54, 3227–3243. https://doi.org/10.1194/jlr.R037762
Adams, V., Besler, C., Fischer, T., Riwanto, M., Noack, F., Höllriegel, R., Oberbach, A., Jehmlich, N., Volker, U., Winzer, E. B., Lenk, K., Hambrecht, R., Schuler, G., Linke, A., Landmesser, U., & Erbs, S. (2013). Exercise training in patients with chronic heart failure promotes restoration of HDL functional properties Circulation Research, 113, 1345–1355. https://doi.org/10.1161/CIRCRESAHA.113.301684
Schönrath, F., Alkadhi, H., Landmesser, U., Falk, V., & Plass, A. (2013). Giant unruptured sinus valsalva aneurysm: an unusual cause of typical angina European Heart Journal, 34, 1608–1608. https://doi.org/10.1093/eurheartj/ehs476
Landmesser, U. (2013). The difficult search for a “partner” of statins in lipid-targeted prevention of vascular events: the re-emergence and fall of niacin. European Heart Journal, 34, 1254–1257. https://doi.org/10.1093/eurheartj/eht064
Jaguszewski, M., Guagliumi, G., & Landmesser, U. (2013). Optical frequency domain imaging for guidance of optimal stenting in the setting of recanalization of chronic total occlusion Journal of Invasive Cardiology, 25, 367–368.
Kränkel, N., Kuschnerus, K., Müller, M., Speer, T., Mocharla, P., Madeddu, P., Bader, M., Lüscher, T. F., & Landmesser, U. (2013). Novel insights into the critical role of bradykinin and the kinin b2 receptor for vascular recruitment of circulating endothelial repair-promoting mononuclear cell subsets: alterations in patients with coronary disease Circulation, 127, 594–603. https://doi.org/10.1161/CIRCULATIONAHA.112.118117
Speer, T., Rohrer, L., Blyszczuk, P., Shroff, R., Kuschnerus, K., Kränkel, N., Kania, G., Zewinger, S., Akhmedov, A., Shi, Y., Martin, T., Perisa, D., Winnik, S., Müller, M. F., Sester, U., Wernicke, G., Jung, A., Gutteck, U., Eriksson, U., … Landmesser, U. (2013). Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2 Immunity, 38, 754–768. https://doi.org/10.1016/j.immuni.2013.02.009
Huang, Y., Wu, Z., Riwanto, M., Gao, S., Levison, B. S., Gu, X., Fu, X., Wagner, M. A., Besler, C., Gerstenecker, G., Zhang, R., Li, X.-M., DiDonato, A. J., Gogonea, V., Tang, W. H. W., Smith, J. D., Plow, E. F., Fox, P. L., Shih, D. M., … Hazen, S. L. (2013). Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex Journal of Clinical Investigation, 123, 3815–3828. https://doi.org/10.1172/JCI67478
Fadini, G. P., de Kreutzenberg, S. V., Boscaro, E., Albiero, M., Cappellari, R., Kränkel, N., Landmesser, U., Toniolo, A., Bolego, C., Cignarella, A., Seeger, F., Dimmeler, S., Zeiher, A., Agostini, C., & Avogaro, A. (2013). An unbalanced monocyte polarisation in peripheral blood and bone marrow of patients with type 2 diabetes has an impact on microangiopathy Diabetologia, 56, 1856–1866. https://doi.org/10.1007/s00125-013-2918-9
Stähli, B. E., Tasnady, H., Lüscher, T. F., Gebhard, C., Mikulicic, F., Erhart, L., Bühler, I., Landmesser, U., Altwegg, L., Wischnewsky, M. B., Grünenfelder, J., Falk, V., Corti, R., & Maier, W. (2013). Early and late mortality in patients undergoing transcatheter aortic valve implantation: Comparison of the Novel EuroScore II with established risk scores Cardiology, 126, 15–23. https://doi.org/10.1159/000351438
Jakob, P., & Landmesser, U. (2013). Current status of cell-based therapy for heart failure Current Heart Failure Reports, 10, 165–176. https://doi.org/10.1007/s11897-013-0134-z
Riwanto, M., Rohrer, L., Roschitzki, B., Besler, C., Landmesser, U., & et al. (2013). Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: role of high-density lipoprotein-proteome remodeling Circulation, 127, 891–904. https://doi.org/10.1161/CIRCULATIONAHA.112.108753
Templin, C., Jaguszewski, M., Ghadri, J. R., Sudano, I., Gaehwiler, R., Hellermann, J. P., Schoenenberger-Berzins, R., Landmesser, U., Erne, P., Noll, G., & Lüscher, T. F. (2013). Vascular lesions induced by renal nerve ablation as assessed by optical coherence tomography: pre- and post-procedural comparison with the Simplicity(R) catheter system and the EnligHTN multi-electrode renal denervation catheter European Heart Journal, 34, 2141–2148. https://doi.org/10.1093/eurheartj/eht141
Albiero, M., Rattazzi, M., Menegazzo, L., Boscaro, E., Cappellari, R., Pagnin, E., Bertacco, E., Poncina, N., Dyar, K., Ciciliot, S., Iwabuchi, K., Millioni, R., Arrigoni, G., Kraenkel, N., Landmesser, U., Agostini, C., Avogaro, A., & Fadini, G. P. (2013). Myeloid calcifying cells promote atherosclerotic calcification via paracrine activity and allograft inflammatory factor-1 overexpression Basic Research in Cardiology, 108, 368. https://doi.org/10.1007/s00395-013-0368-7
Breitenstein, A., Wyss, C. A., Spescha, R. D., Franzeck, F. C., Hof, D., Riwanto, M., Hasun, M., Akhmedov, A., von Eckardstein, A., Maier, W., Landmesser, U., Lüscher, T. F., & Camici, G. G. (2013). Peripheral blood monocyte Sirt1 expression is reduced in patients with coronary artery disease PLoS ONE, 8, e53106. https://doi.org/10.1371/journal.pone.0053106
Silbernagel, G., Schöttker, B., Appelbaum, S., Scharnagl, H., Kleber, M. E., Grammer, T. B., Ritsch, A., Mons, U., Holleczek, B., Goliasch, G., Niessner, A., Boehm, B. O., Schnabel, R. B., Brenner, H., Blankenberg, S., Landmesser, U., & März, W. (2013). High-density lipoprotein cholesterol, coronary artery disease, and cardiovascular mortality European Heart Journal, 34, 3563–3571. https://doi.org/10.1093/eurheartj/eht343
Jakob, P., & Landmesser, U. (2012). Role of microRNAs in stem/progenitor cells and cardiovascular repair Cardiovascular Research, 93, 614–622. https://doi.org/10.1093/cvr/cvr311
Jakob, P., Doerries, C., Briand, S., Mocharla, P., Kränkel, N., Besler, C., Mueller, M., Manes, C., Templin, C., Baltes, C., Rudin, M., Adams, H., Wolfrum, M., Noll, G., Ruschitzka, F., Lüscher, T. F., & Landmesser, U. (2012). Loss of AngiomiR-126 and 130a in Angiogenic Early Outgrowth Cells from Patients with Chronic Heart Failure: Role for Impaired in vivo Neovascularization and Cardiac Repair Capacity Circulation, 126, 2962–2975. https://doi.org/10.1161/CIRCULATIONAHA.112.093906
Lüscher, T. F., Gersh, B., Hendricks, G., Landmesser, U., Ruschitzka, F., & Wijns, W. (2012). The best of the European Heart Journal: look back with pride European Heart Journal, 33, 1161–1171. https://doi.org/10.1093/eurheartj/ehs098
Stähli, B. E., Grünenfelder, J., Jacobs, S., Falk, V., Landmesser, U., Wischnewsky, M. B., Lüscher, T. F., Corti, R., Maier, W., & Altwegg, L. A. (2012). Assessment of inflammatory response to transfemoral transcatheter aortic valve implantation compared to transapical and surgical procedures: a pilot study Journal of Invasive Cardiology, 24, 407–411. http://www.invasivecardiology.com/articles/assessment-inflammatory-response-transfemoral-transcatheter-aortic-valve-implantation-compa
Fiechter, M., Ghadri, J. R., Sidler, M., Martin, U., Landmesser, U., Kaufmann, P. A., Lüscher, T. F., & Templin, C. (2012). Cardiac quadruple-fusion imaging: a brief report on a novel integrated multimodality approach for in vivo visualization of transplanted stem cells International Journal of Cardiology, 161, 62–63. https://doi.org/10.1016/j.ijcard.2012.06.039
Landmesser, U. (2012). High Density Lipoprotein - Should we Raise it? Current Vascular Pharmacology, 10, 718–719. https://doi.org/10.2174/157016112803520710
Wojakowski, W., Landmesser, U., Bachowski, R., Jadczyk, T., & Tendera, M. (2012). Mobilization of stem and progenitor cells in cardiovascular diseases Leukemia, 26, 23–33. https://doi.org/10.1038/leu.2011.184
Besler, C., Lüscher, T. F., & Landmesser, U. (2012). Molecular mechanisms of vascular effects of High-density lipoprotein: alterations in cardiovascular disease EMBO Molecular Medicine, 4, 251–268. https://doi.org/10.1002/emmm.201200224
Landmesser, U., von Eckardstein, A., Kastelein, J., Deanfield, J., & Lüscher, T. F. (2012). Increasing high-density lipoprotein cholesterol by cholesteryl ester transfer protein-inhibition: a rocky road and lessons learned? The early demise of the dal-HEART programme European Heart Journal, 33, 1712–1715. https://doi.org/10.1093/eurheartj/ehs182
Templin, C., Zweigerdt, R., Schwanke, K., Olmer, R., Ghadri, J.-R., Emmert, M. Y., Müller, E., Küest, S. M., Cohrs, S., Schibli, R., Kronen, P. W., Hilbe, M., Reinisch, A., Strunk, D., Haverich, A., Hoerstrup, S., Lüscher, T. F., Kaufmann, P. A., Landmesser, U., & Martin, U. (2012). Transplantation and tracking of human-induced pluripotent stem cells in a pig model of myocardial infarction: assessment of cell survival, engraftment, and distribution by hybrid single photon emission computed tomography/computed tomography of sodium iodide symporter transgene expression Circulation, 126, 430–439. https://doi.org/10.1161/CIRCULATIONAHA.111.087684
Landmesser, U. (2012). Optical coherence tomography (OCT) evaluation after coronary stenting: the “black hole” and other low OCT signal-intensity areas. EuroIntervention, 7, 1367–1371. https://doi.org/10.4244/EIJV7I12A215
Lüscher, T. F., Ruschitzka, F., Landmesser, U., Voors, A. A., van Gilst, W. H., & van Veldhuisen, D. J. (2012). The European Heart Journal and the European Journal of Heart Failure: partners in scientific publishing European Journal of Heart Failure, 14, 1075–1082. https://doi.org/10.1093/eurjhf/hfs137
Saguner, A. M., Haegeli, L. M., Templin, C., Wolber, T., Landmesser, U., & Duru, F. (2012). Arrhythmogenic cardiomyopathy suspected by electrocardiogram: confirmed by angiography European Heart Journal, 33, 1343. https://doi.org/10.1093/eurheartj/ehs087
Lüscher, T. F., Landmesser, U., Wolfrum, M., Noll, G., & Sudano, I. (2012). Interventional treatment of essential hypertension: renal sympathetic denervation In E. Eeckout, P. W. Serruys, W. Wijns, A. Vahanian, M. R. H. M. van Sambeek, & R. De Palma (Eds.), Percutaneous Interventional Cardiovascular Medicine: The PCR-EAPCI Textbook (p. online). Europa Edition.
Kränkel, N., Lüscher, T. F., & Landmesser, U. (2012). “Endothelial progenitor cells” as a therapeutic strategy in cardiovascular disease. Current Vascular Pharmacology, 10, 107–124. https://doi.org/10.2174/157016112798829832
Landmesser, U., & Holmes, D. R. (2012). Left atrial appendage closure: a percutaneous transcatheter approach for stroke prevention in atrial fibrillation European Heart Journal, 33, 698–704. https://doi.org/10.1093/eurheartj/ehr393
Sonnenschein, K., Horvàth, T., Mueller, M., Markowski, A., Siegmund, T., Jacob, C., Drexler, H., & Landmesser, U. (2011). Exercise training improves in vivo endothelial repair capacity of early endothelial progenitor cells in subjects with metabolic syndrome European Journal of Preventive Cardiology, 18, 406–414. https://doi.org/10.1177/1741826710389373
Besler, C., Heinrich, K., Rohrer, L., Doerries, C., Riwanto, M., Shih, D. M., Chroni, A., Yonekawa, K., Stein, S., Schaefer, N., Mueller, M., Akhmedov, A., Daniil, G., Manes, C., Templin, C., Wyss, C., Maier, W., Tanner, F. C., Matter, C. M., … Landmesser, U. (2011). Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease Journal of Clinical Investigation, 121, 2693–2708. https://doi.org/10.1172/JCI42946
Kania, G., Boheler, K. R., Landmesser, U., & Wojakowski, W. (2011). Stem cells in heart failure Stem Cells International, 2011, 193918. https://doi.org/10.4061/2011/193918
Templin, C., Lüscher, T. F., & Landmesser, U. (2011). Cell-based cardiovascular repair and regeneration in acute myocardial infarction and chronic ischemic cardiomyopathy-current status and future developments The International Journal of Developmental Biology, 55, 407–417. https://doi.org/10.1387/ijdb.103219ct
Templin, C., Kränkel, N., Lüscher, T. F., & Landmesser, U. (2011). Stem cells in cardiovascular regeneration: from preservation of endogenous repair to future cardiovascular therapies. Current Pharmaceutical Design, 17, 3280–3294. https://doi.org/10.2174/138161211797904190
Sorrentino, S. A., Doerries, C., Manes, C., Speer, T., Dessy, C., Lobysheva, I., Mohmand, W., Akbar, R., Bahlmann, F., Besler, C., Schaefer, A., Hilfiker-Kleiner, D., Lüscher, T. F., Balligand, J. L., Drexler, H., & Landmesser, U. (2011). Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade Journal of the American College of Cardiology, 57, 601–611. https://doi.org/10.1016/j.jacc.2010.09.037
Valenta, I., Landmesser, U., & Schindler, T. H. (2011). Vascular function of the peripheral and coronary circulation: worthwhile to assess their relation? Journal of Nuclear Cardiology, 18, 201–203. https://doi.org/10.1007/s12350-011-9357-0
Gielen, S., & Landmesser, U. (2011). A new look at HDL in coronary disease: can we escape natural history? Heart, 97, 1899–1901. https://doi.org/10.1136/heartjnl-2011-300612
Rozenberg, I., Sluka, S. H. M., Mocharla, P., Hallenberg, A., Rotzius, P., Borén, J., Kränkel, N., Landmesser, U., Borsig, L., Lüscher, T. F., Eriksson, E. E., & Tanner, F. C. (2011). Deletion of L-selectin increases atherosclerosis development in ApoE-/- mice PLoS ONE, 6, e21675. https://doi.org/10.1371/journal.pone.0021675
Hasun, M., Manka, R., Lüscher, T. F., & Landmesser, U. (2011). Dizziness and pre-syncope: an unusual clinical presentation of a spontaneous coronary artery dissection as revealed by optical coherence tomography Journal of the American College of Cardiology, 58, 1191. https://doi.org/10.1016/j.jacc.2010.11.087
Tongers, J., Losordo, D. W., & Landmesser, U. (2011). Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges European Heart Journal, 32, 1197–1206. https://doi.org/10.1093/eurheartj/ehr018
Kränkel, N., Kuschnerus, K., Madeddu, P., Lüscher, T. F., & Landmesser, U. (2011). A novel flow cytometry-based assay to study leukocyte-endothelial cell interactions in vitro Cytometry. Part A, 79, 256–262. https://doi.org/10.1002/cyto.a.21043
Ghadri, J. R., Fiechter, M., Templin, C., Lüscher, T. F., Kaufmann, P. A., & Landmesser, U. (2011). Cardiac hybrid imaging in a patient with a single coronary artery originating from the right sinus of Valsalva European Heart Journal, 32, 2757. https://doi.org/10.1093/eurheartj/ehr273
Salzberg, S. P., Emmert, M. Y., Starck, C. T., & Landmesser, U. E. (2011). Review of the field of left atrial appendage occlusion devices (No. CH096-098; Franco).
Lekakis, J., Abraham, P., Balbarini, A., Blann, A., Boulanger, C. M., Cockcroft, J., Cosentino, F., Deanfield, J., Gallino, A., Ikonomidis, I., Kremastinos, D., Landmesser, U., Protogerou, A., Stefanadis, C., Tousoulis, D., Vassalli, G., Vink, H., Werner, N., Wilkinson, I., & Vlachopoulos, C. (2011). Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation European Journal of Preventive Cardiology, 18, 775–789. https://doi.org/10.1177/1741826711398179
Doehner, W., & Landmesser, U. (2011). Xanthine oxidase and uric acid in cardiovascular disease: clinical impact and therapeutic options Seminars in Nephrology, 31, 433–440. https://doi.org/10.1016/j.semnephrol.2011.08.007
Pazhenkottil, A. P., Herzog, B. A., Husmann, L., Buechel, R. R., Burger, I. A., Valenta, I., Landmesser, U., Wyss, C. A., & Kaufmann, P. A. (2010). Non-invasive assessment of coronary artery disease with CT coronary angiography and SPECT: a novel dose-saving fast-track algorithm European Journal of Nuclear Medicine and Molecular Imaging, 37, 522–527. https://doi.org/10.1007/s00259-009-1273-z
Husmann, L., Herzog, B. A., Burger, I. A., Buechel, R. R., Pazhenkottil, A. P., von Schulthess, P., Wyss, C. A., Gaemperli, O., Landmesser, U., & Kaufmann, P. A. (2010). Usefulness of additional coronary calcium scoring in low-dose CT coronary angiography with prospective ECG-triggering impact on total effective radiation dose and diagnostic accuracy Academic Radiology, 17, 201–206. https://doi.org/10.1016/j.acra.2009.09.007
Sudano, I., Flammer, A. J., Périat, D., Enseleit, F., Hermann, M., Wolfrum, M., Hirt, A., Kaiser, P., Hurlimann, D., Neidhart, M., Gay, S., Holzmeister, J., Nussberger, J., Mocharla, P., Landmesser, U., Haile, S. R., Corti, R., Vanhoutte, P. M., Lüscher, T. F., … Ruschitzka, F. (2010). Acetaminophen increases blood pressure in patients with coronary artery disease Circulation, 122, 1789–1796. https://doi.org/10.1161/CIRCULATIONAHA.110.956490
Zuchi, C., Ambrosio, G., Lüscher, T. F., & Landmesser, U. (2010). Nutraceuticals in cardiovascular prevention: lessons from studies on endothelial function Cardiovascular Therapeutics, 28, 187–201. https://doi.org/10.1111/j.1755-5922.2010.00165.x
Sorrentino, S. A., Besler, C., Rohrer, L., Meyer, M., Heinrich, K., Bahlmann, F. H., Mueller, M., Horváth, T., Doerries, C., Heinemann, M., Flemmer, S., Markowski, A., Manes, C., Bahr, M. J., Haller, H., von Eckardstein, A., Drexler, H., & Landmesser, U. (2010). Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy Circulation, 121, 110–122. https://doi.org/10.1161/CIRCULATIONAHA.108.836346
Stein, S., Schäfer, N., Breitenstein, A., Besler, C., Winnik, S., Lohmann, C., Heinrich, K., Brokopp, C. E., Handschin, C., Landmesser, U., Tanner, F. C., Lüscher, T. F., & Matter, C. M. (2010). SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice Aging, 2, 353–360. https://doi.org/10.18632/aging.100162
Templin, C., Lüscher, T. F., & Landmesser, U. (2010). Stamm- und progenitorzellbasierte Therapieansätze. Aktuelle Entwicklungen zur Behandlung des akuten Myokardinfarkts und der chronischen ischämischen Kardiomyopathie Herz, 35, 445–456. https://doi.org/10.1007/s00059-010-3397-0
Stein, S., Lohmann, C., Schäfer, N., Hofmann, J., Rohrer, L., Besler, C., Rothgiesser, K. M., Becher, B., Hottiger, M. O., Borén, J., McBurney, M. W., Landmesser, U., Lüscher, T. F., & Matter, C. M. (2010). SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis European Heart Journal, 31, 2301–2309. https://doi.org/10.1093/eurheartj/ehq107
Templin, C., Meyer, M., Müller, M. F., Djonov, V., Hlushchuk, R., Dimova, I., Flueckiger, S., Kronen, P., Sidler, M., Klein, K., Nicholls, F., Ghadri, J. R., Weber, K., Paunovic, D., Corti, R., Hoerstrup, S. P., Lüscher, T. F., & Landmesser, U. (2010). Coronary optical frequency domain imaging (OFDI) for in vivo evaluation of stent healing: comparison with light and electron microscopy European Heart Journal, 31, 1792–1801. https://doi.org/10.1093/eurheartj/ehq168
Lüscher, T. F., Landmesser, U., & Ruschitzka, F. (2010). Standing firm - the European Heart Journal, scientific controversies and the industry European Heart Journal, 31, 1157–1158. https://doi.org/10.1093/eurheartj/ehq127
Besler, C., Heinrich, K., Riwanto, M., Lüscher, T. F., & Landmesser, U. (2010). High-density lipoprotein-mediated anti-atherosclerotic and endothelial-protective effects: a potential novel therapeutic target in cardiovascular disease Current Pharmaceutical Design, 16, 1480–1493. https://doi.org/10.2174/138161210791051013
Sürder, D., Schwitter, J., Moccetti, T., Astori, G., Rufibach, K., Plein, S., Cicero, V. L., Soncin, S., Windecker, S., Moschovitis, A., Wahl, A., Erne, P., Jamshidi, P., Auf der Maur, C., Manka, R., Soldati, G., Bühler, I., Wyss, C., Landmesser, U., … Corti, R. (2010). Cell-based therapy for myocardial repair in patients with acute myocardial infarction: rationale and study design of the SWiss multicenter Intracoronary Stem cells Study in Acute Myocardial Infarction (SWISS-AMI) American Heart Journal, 160, 58–64. https://doi.org/10.1016/j.ahj.2010.03.039
Giannotti, G., Doerries, C., Mocharla, P. S., Mueller, M. F., Bahlmann, F. H., Horvàth, T., Jiang, H., Sorrentino, S. A., Steenken, N., Manes, C., Marzilli, M., Rudolph, K. L., Lüscher, T. F., Drexler, H., & Landmesser, U. (2010). Impaired endothelial repair capacity of early endothelial progenitor cells in prehypertension: relation to endothelial dysfunction Hypertension, 55, 1389–1397. https://doi.org/10.1161/HYPERTENSIONAHA.109.141614
Templin, C., Ghadri, J. R., Wyss, C., Lüscher, T. F., Kaufmann, P., & Landmesser, U. (2010). Severe left main coronary stenosis and mitral regurgitation in a young female patient without cardiovascular risk factors 14 years after mediastinal radiation therapy Clinical Research in Cardiology, 99, 199–201. https://doi.org/10.1007/s00392-009-0103-4
Lüscher, T. F., Brugada, J., Gersh, B. J., Landmesser, U., Serruys, P. W., Murphy, S., Dedecke, S., Rogers, S., & Ruschitzka, F. (2010). Happy birthday European Heart Journal: in 30 years, from Cinderella to centre stage European Heart Journal, 31, 1945–1950. https://doi.org/10.1093/eurheartj/ehq243
Herzog, B. A., Wyss, C. A., Husmann, L., Gaemperli, O., Valenta, I., Treyer, V., Landmesser, U., & Kaufmann, P. A. (2009). First Head-to-Head Comparison of Effective Radiation Dose from Low-Dose CT with Prospective ECG-Triggering versus Invasive Coronary Angiography Heart, 95, 1656–1661. https://doi.org/10.1136/hrt.2008.162420
Husmann, L., Herzog, B. A., Burkhard, N., Tatsugami, F., Valenta, I., Gaemperli, O., Wyss, C. A., Landmesser, U., & Kaufmann, P. A. (2009). Body physique and heart rate variability determine the occurrence of stair-step artefacts in 64-slice CT coronary angiography with prospective ECG-triggering European Radiology, 19, 1698–1703. https://doi.org/10.1007/s00330-009-1339-0
Germano, D., Blyszczuk, P., Valaperti, A., Kania, G., Dirnhofer, S., Landmesser, U., Lüscher, T. F., Hunziker, L., Zulewski, H., & Eriksson, U. (2009). Prominin-1/CD133+ lung epithelial progenitors protect from bleomycin-induced pulmonary fibrosis American Journal of Respiratory and Critical Care Medicine, 179, 939–949. https://doi.org/10.1164/rccm.200809-1390OC
Herzog, B. A., Husmann, L., Valenta, I., Tay, F. M., Burkhard, N., Gaemperli, O., Wyss, C. A., Landmesser, U., & Kaufmann, P. A. (2009). Determinants of vessel contrast in BMI-adapted low dose CT coronary angiography with prospective ECG-triggering International Journal of Cardiovascular Imaging, 25, 625–630. https://doi.org/10.1007/s10554-009-9460-3
Husmann, L., Herzog, B. A., Gaemperli, O., Tatsugami, F., Burkhard, N., Valenta, I., Veit-Haibach, P., Wyss, M. T., Landmesser, U., & Kaufmann, P. A. (2009). Diagnostic accuracy of computed tomography coronary angiography and evaluation of stress-only single-photon emission computed tomography/computed tomography hybrid imaging: comparison of prospective electrocardiogram-triggering vs. retrospective gating European Heart Journal, 30, 600–607. https://doi.org/10.1093/eurheartj/ehn536
Landmesser, U., Wollert, K. C., & Drexler, H. (2009). Potential novel pharmacological therapies for myocardial remodelling Cardiovascular Research, 81, 519–527. https://doi.org/10.1093/cvr/cvn317
Templin, C., Grote, K., Schledzewski, K., Ghadri, J. R., Schnabel, S., Napp, L. C., Schieffer, B., Kurzen, H., Goerdt, S., Landmesser, U., Koenen, W., & Faulhaber, J. (2009). Ex vivo expanded haematopoietic progenitor cells improve dermal wound healing by paracrine mechanisms Experimental Dermatology, 18, 445–453. https://doi.org/10.1111/j.1600-0625.2008.00809.x
Charakida, M., Besler, C., Batuca, J. R., Sangle, S., Marques, S., Sousa, M., Wang, G., Tousoulis, D., Delgado Alves, J., Loukogeorgakis, S. P., Mackworth-Young, C., D’Cruz, D., Luscher, T., Landmesser, U., & Deanfield, J. E. (2009). Vascular abnormalities, paraoxonase activity, and dysfunctional HDL in primary antiphospholipid syndrome JAMA: The Journal of the American Medical Association, 302, 1210–1217. https://doi.org/10.1001/jama.2009.1346
Gardiwal, A., Reissmann, L. M., Kotlarz, D., Oswald, H., Korte, T., Landmesser, U., Klein, G., & Templin, C. (2009). Arrhythmia susceptibility in mice after therapy with beta-catenin-transduced hematopoietic progenitor cells after myocardial ischemia/reperfusion Cardiology, 114, 199–207. https://doi.org/10.1159/000228644
Lüscher, T. F., Gersch, B., Brugada, J., Landmesser, U., Ruschitzka, F., & Serruys, P. W. (2009). The European Heart Journal goes global: the road ahead of the editorial team 2009-2011 European Heart Journal, 30, 1–5. https://doi.org/10.1093/eurheartj/ehn549
Herzog, B. A., Husmann, L., Landmesser, U., & Kaufmann, P. A. (2009). Low-dose computed tomography coronary angiography and myocardial perfusion imaging: cardiac hybrid imaging below 3mSv European Heart Journal, 30, 644. https://doi.org/10.1093/eurheartj/ehn490
Landmesser, U. (2009). Bone marrow cell therapy after myocardial infarction. What should we select? European Heart Journal, 30, 1310–1312. https://doi.org/10.1093/eurheartj/ehp181
Herzog, B. A., Husmann, L., Burkhard, N., Valenta, I., Gaemperli, O., Tatsugami, F., Wyss, C. A., Landmesser, U., & Kaufmann, P. A. (2009). Low-dose CT coronary angiography using prospective ECG-triggering: impact of mean heart rate and heart rate variability on image quality Academic Radiology, 16, 15–21. https://doi.org/10.1016/j.acra.2008.06.010
Herzog, B. A., Husmann, L., Burkhard, N., Gaemperli, O., Valenta, I., Tatsugami, F., Wyss, C. A., Landmesser, U., & Kaufmann, P. A. (2008). Accuracy of low-dose computed tomography coronary angiography using prospective electrocardiogram-triggering: first clinical experience European Heart Journal, 29, 3037–3042. https://doi.org/10.1093/eurheartj/ehn485
Doehner, W., Springer, J., Landmesser, U., Struthers, A. D., & Anker, S. D. (2008). Uric acid in chronic heart failure - current pathophysiological concepts European Journal of Heart Failure, 10, 1269–1270. https://doi.org/10.1016/j.ejheart.2008.10.005
Gongora, M. C., Lob, H. E., Landmesser, U., Guzik, T. J., Martin, W. D., Ozumi, K., Wall, S. M., Wilson, D. S., Murthy, N., Gravanis, M., Fukai, T., & Harrison, D. G. (2008). Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome American Journal of Pathology, 173, 915–926. https://doi.org/10.2353/ajpath.2008.080119
Besler, C., Doerries, C., Giannotti, G., Luescher, T. F., & Landmesser, U. (2008). Pharmacological approaches to improve endothelial repair mechanisms Expert Review of Cardiovascular Therapy, 6, 1071–1082. https://doi.org/10.1586/14779072.6.8.1071
Salguero, G., Akin, E., Templin, C., Kotlarz, D., Doerries, C., Landmesser, U., Grote, K., & Schieffer, B. (2008). Renovascular hypertension by two-kidney one-clip enhances endothelial progenitor cell mobilization in a p47phox-dependent manner Journal of Hypertension, 26, 257–268. https://doi.org/10.1097/HJH.0b013e3282f09f79
Templin, C., Kotlarz, D., Faulhaber, J., Schnabel, S., Grote, K., Salguero, G., Luchtefeld, M., Hiller, K. H., Jakob, P., Naim, H. Y., Schieffer, B., Hilfiker-Kleiner, D., Landmesser, U., Limbourg, F. P., & Drexler, H. (2008). Ex vivo expanded hematopoietic progenitor cells improve cardiac function after myocardial infarction: role of beta-catenin transduction and cell dose Journal of Molecular and Cellular Cardiology, 45, 394–403. https://doi.org/10.1016/j.yjmcc.2008.06.010
Giannotti, Gianna; Landmesser, Ulf (2007). Endothelial dysfunction as an early sign of atherosclerosis Herz, 32(7):568-572.
Sorrentino, S. A., Bahlmann, F. H., Besler, C., Müller, M., Schulz, S., Kirchhoff, N., Doerries, C., Horváth, T., Limbourg, A., Limbourg, F., Fliser, D., Haller, H., Drexler, H., & Landmesser, U. (2007). Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone Circulation, 116, 163–173. https://doi.org/10.1161/CIRCULATIONAHA.106.684381
Fischer, D., Landmesser, U., Spiekermann, S., Hilfiker-Kleiner, D., Hospely, M., Müller, M., Busse, R., Fleming, I., & Drexler, H. (2007). Cytochrome P450 2C9 is involved in flow-dependent vasodilation of peripheral conduit arteries in healthy subjects and in patients with chronic heart failure European Journal of Heart Failure, 9, 770–775. https://doi.org/10.1016/j.ejheart.2007.05.005

Shroff, R. et al. HDL in Children with CKD Promotes Endothelial Dysfunction and an Abnormal Vascular Phenotype. Journal of the American Society of Nephrology : JASN 25, 2658-2668, doi:10.1681/ASN.2013111212 (2014).

Landmesser, U. Coronary artery disease: HDL and coronary heart disease--novel insights. Nature reviews. Cardiology 11, 559-560, doi:10.1038/nrcardio.2014.128 (2014).

Kratzer, A., Giral, H. & Landmesser, U. High-density lipoproteins as modulators of endothelial cell functions: alterations in patients with coronary artery disease. Cardiovascular research 103, 350-361, doi:10.1093/cvr/cvu139 (2014).

Krankel, N., Luscher, T. F. & Landmesser, U. Novel insights into vascular repair mechanisms. Current pharmaceutical design 20, 2430-2438 (2014).

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Kyburz D, Karouzakis E, Ospelt C. Epigenetic changes: the missing link. Best Pract Res Clin Rheumatol. 2014 Aug;28(4):577-587.

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